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Simple IHC reveals complex MMR alternations than PCR assays: Validation by LCM and next‐generation sequencing
Evaluation of the status of mismatch repair (MMR) in tumors is crucial for determining the application of immune checkpoint inhibitors (ICIs). Conventional PCR (MSI‐PCR) is the gold standard for confirming the MMR status. However, it requires visual confirmation and presents difficulties in determin...
Autores principales: | Amemiya, Kenji, Hirotsu, Yosuke, Nagakubo, Yuki, Watanabe, Shunsuke, Amemiya, Saki, Mochizuki, Hitoshi, Oyama, Toshio, Kondo, Tetsuo, Omata, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741978/ https://www.ncbi.nlm.nih.gov/pubmed/35596629 http://dx.doi.org/10.1002/cam4.4832 |
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