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Anti‐pruritic effect of isothiocyanates: Potential involvement of toll‐like receptor 3 signaling

The innate immune system has an emerging role as a mediator of neuro‐immune communication and a therapeutic target for itch. Toll‐like receptor 3 (TLR3) plays an important role in itch, as shown in TLR3 knock‐out mice. In this study, to evaluate effects of TLR3 inhibitors on histamine‐independent it...

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Detalles Bibliográficos
Autores principales: Moriyama, Masaki, Konno, Mitsuhiro, Serizawa, Kanako, Yuzawa, Natsumi, Majima, Yuki, Hayashi, Ikuo, Suzuki, Tomohiko, Kainoh, Mie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741980/
https://www.ncbi.nlm.nih.gov/pubmed/36507603
http://dx.doi.org/10.1002/prp2.1038