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Development of LC-HRMS Untargeted Analysis Methods for Nasal Epithelial Lining Fluid Exposomics

BACKGROUND: The nasal mucosa, as a primary site of entry for inhaled substances, contains both inhaled xenobiotic and endogenous biomarkers. Nasal mucosa can be non-invasively sampled (nasal epithelial lining fluid “NELF”) and analyzed for biological mediators. However, methods for untargeted analys...

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Detalles Bibliográficos
Autores principales: Hsiao, Yun-Chung, Liu, Chih-Wei, Robinette, Carole, Knight, Noelle, Lu, Kun, Rebuli, Meghan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742129/
https://www.ncbi.nlm.nih.gov/pubmed/35750751
http://dx.doi.org/10.1038/s41370-022-00448-3