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Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how anti-mycobacterial drugs facilitate the emergence of bacterial populations that survive throughout treatment. Using static kill curve experimen...

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Detalles Bibliográficos
Autores principales: Kloprogge, Frank, Ortiz Canseco, Julio, Phee, Lynette, Sadouki, Zahra, Kipper, Karin, Witney, Adam A., Stoker, Neil, McHugh, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742156/
https://www.ncbi.nlm.nih.gov/pubmed/36504241
http://dx.doi.org/10.1038/s41598-022-25827-6