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Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis
Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how anti-mycobacterial drugs facilitate the emergence of bacterial populations that survive throughout treatment. Using static kill curve experimen...
Autores principales: | Kloprogge, Frank, Ortiz Canseco, Julio, Phee, Lynette, Sadouki, Zahra, Kipper, Karin, Witney, Adam A., Stoker, Neil, McHugh, Timothy D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742156/ https://www.ncbi.nlm.nih.gov/pubmed/36504241 http://dx.doi.org/10.1038/s41598-022-25827-6 |
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