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Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies

The human immunoglobulin heavy-chain (IGH) locus is exceptionally polymorphic, with high levels of allelic and structural variation. Thus, germline IGH genotypes are personal, which may influence responses to infection and vaccination. For an improved understanding of inter-individual differences in...

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Detalles Bibliográficos
Autores principales: Pushparaj, Pradeepa, Nicoletto, Andrea, Sheward, Daniel J., Das, Hrishikesh, Castro Dopico, Xaquin, Perez Vidakovics, Laura, Hanke, Leo, Chernyshev, Mark, Narang, Sanjana, Kim, Sungyong, Fischbach, Julian, Ekström, Simon, McInerney, Gerald, Hällberg, B. Martin, Murrell, Ben, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742198/
https://www.ncbi.nlm.nih.gov/pubmed/36574772
http://dx.doi.org/10.1016/j.immuni.2022.12.005