Lacosamide decreases neonatal seizures without increasing apoptosis

OBJECTIVE: Many seizing neonates fail to respond to first‐line anticonvulsant medications. Phenobarbital, an allosteric modulator of γ‐aminobutyric acid type A (GABA(A)) receptors, has low efficacy in treating neonatal seizures and causes neuronal apoptosis. Nonetheless, it is one of the most used a...

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Detalles Bibliográficos
Autores principales: Langton, Rachel L., Sharma, Shaunik, Tiarks, Grant C., Bassuk, Alexander G., Glykys, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742288/
https://www.ncbi.nlm.nih.gov/pubmed/36168798
http://dx.doi.org/10.1111/epi.17423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742288/
https://www.ncbi.nlm.nih.gov/pubmed/36168798
http://dx.doi.org/10.1111/epi.17423

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