From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders

A novel class of benzyl-free and benzyl-substituted carbamylated tryptamine derivatives (CDTs) was designed and synthesized to serve as effective building blocks for the development of novel multi-target directed ligands (MTDLs) for the treatment of neurological disorders linked to cholinesterase (C...

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Detalles Bibliográficos
Autores principales: Wu, Junbo, Zhang, Honghua, Wang, Yuying, Yin, Gaofeng, Li, Qien, Zhuo, Linsheng, Chen, Hongjin, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742383/
https://www.ncbi.nlm.nih.gov/pubmed/36518670
http://dx.doi.org/10.3389/fphar.2022.1036030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742383/
https://www.ncbi.nlm.nih.gov/pubmed/36518670
http://dx.doi.org/10.3389/fphar.2022.1036030

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