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From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders
A novel class of benzyl-free and benzyl-substituted carbamylated tryptamine derivatives (CDTs) was designed and synthesized to serve as effective building blocks for the development of novel multi-target directed ligands (MTDLs) for the treatment of neurological disorders linked to cholinesterase (C...
Autores principales: | Wu, Junbo, Zhang, Honghua, Wang, Yuying, Yin, Gaofeng, Li, Qien, Zhuo, Linsheng, Chen, Hongjin, Wang, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742383/ https://www.ncbi.nlm.nih.gov/pubmed/36518670 http://dx.doi.org/10.3389/fphar.2022.1036030 |
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