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Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway

Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to high rates of morbidity and mortality. Cinobufagin, a primary component isolated from cinobufotalin, exerts strong anticancer effects. However, there are few reports on its role in...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Mei, Xianghuang, Wu, Yanrong, Yang, Yuting, Zeng, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742439/
https://www.ncbi.nlm.nih.gov/pubmed/36518680
http://dx.doi.org/10.3389/fphar.2022.994625