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Tuning gold-based surface functionalization for streptavidin detection: A combined simulative and experimental study

A rationally designed gold-functionalized surface capable of capturing a target protein is presented using the biotin–streptavidin pair as a proof-of-concept. We carried out multiscale simulations to shed light on the binding mechanism of streptavidin on four differently biotinylated surfaces. Brown...

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Detalles Bibliográficos
Autores principales: Dutta, Sutapa, Gagliardi, Mariacristina, Bellucci, Luca, Agostini, Matteo, Corni, Stefano, Cecchini, Marco, Brancolini, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742443/
https://www.ncbi.nlm.nih.gov/pubmed/36518849
http://dx.doi.org/10.3389/fmolb.2022.1006525