Case report: Complete response to pembrolizumab in a liver metastatic colon adenocarcinoma patient with a novel likely pathogenic germline MSH2 mutation

Lynch syndrome (LS) is a genetic disorder mainly caused by germline mutations in mismatched repair (MMR) genes (MSH2, MLH1, MSH6, and PMS2) or deletions of the epithelial cell adhesion molecule gene (EPCAM). A 43-year-old Chinese male patient underwent radical surgery and was pathologically confirme...

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Detalles Bibliográficos
Autores principales: Xu, Yanjie, Li, Qin, Zhao, Jiemin, Ni, Xuefeng, Li, Ping, Hu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742472/
https://www.ncbi.nlm.nih.gov/pubmed/36518767
http://dx.doi.org/10.3389/fimmu.2022.1064488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742472/
https://www.ncbi.nlm.nih.gov/pubmed/36518767
http://dx.doi.org/10.3389/fimmu.2022.1064488

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