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Case report: Complete response to pembrolizumab in a liver metastatic colon adenocarcinoma patient with a novel likely pathogenic germline MSH2 mutation

Lynch syndrome (LS) is a genetic disorder mainly caused by germline mutations in mismatched repair (MMR) genes (MSH2, MLH1, MSH6, and PMS2) or deletions of the epithelial cell adhesion molecule gene (EPCAM). A 43-year-old Chinese male patient underwent radical surgery and was pathologically confirme...

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Detalles Bibliográficos
Autores principales:	Xu, Yanjie, Li, Qin, Zhao, Jiemin, Ni, Xuefeng, Li, Ping, Hu, Wenwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742472/ https://www.ncbi.nlm.nih.gov/pubmed/36518767 http://dx.doi.org/10.3389/fimmu.2022.1064488

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