Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin α(v)β(3) antagonist

We have recently reported on the development of fb-PMT (NP751), a conjugate of the thyroid hormone metabolite tetraiodothyroacetic acid (tetrac) and monodisperse polyethylene glycol 36. It exhibited high affinity for thyrointegrin α(v)β(3) receptor and potent anti-angiogenic and anticancer activity...

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Detalles Bibliográficos
Autores principales: Fujioka, Kazutoshi, Hay, Bruce A., Godugu, Kavitha, Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742531/
https://www.ncbi.nlm.nih.gov/pubmed/36518666
http://dx.doi.org/10.3389/fphar.2022.902141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742531/
https://www.ncbi.nlm.nih.gov/pubmed/36518666
http://dx.doi.org/10.3389/fphar.2022.902141

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