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New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice

OBJECTIVE(S): The study was aimed at synthesis of the new derivatives of the pyrazolone nucleus, and their spectroscopic and pharmacological analysis and evaluation. MATERIALS AND METHODS: Three series of compounds, with 2-picolinic acid (I a-d), 3-picolinic acid (II a-d), and 4-picolinic acid (III...

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Detalles Bibliográficos
Autores principales: Kanwal, Madiha, Sarwar, Sadia, Nadeem, Humaira, Ata, Athar, Shah, Fawad A., Malik, Sumra, Maqsood, Saima, Miana, Ghulam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742570/
https://www.ncbi.nlm.nih.gov/pubmed/36544531
http://dx.doi.org/10.22038/IJBMS.2022.62869.13912