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In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into understanding and minimising the excruciating effect...

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Detalles Bibliográficos
Autores principales: Lim, Sharoen Yu Ming, Loo, Jason Siau Ee, Alshagga, Mustafa, Alshawsh, Mohammed Abdullah, Ong, Chin Eng, Pan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742833/
https://www.ncbi.nlm.nih.gov/pubmed/36518400
http://dx.doi.org/10.1016/j.toxrep.2022.03.040