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In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into understanding and minimising the excruciating effect...
Autores principales: | Lim, Sharoen Yu Ming, Loo, Jason Siau Ee, Alshagga, Mustafa, Alshawsh, Mohammed Abdullah, Ong, Chin Eng, Pan, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742833/ https://www.ncbi.nlm.nih.gov/pubmed/36518400 http://dx.doi.org/10.1016/j.toxrep.2022.03.040 |
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