Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib

Herbal products are widely used in cancer patients via co−administration with chemotherapy. Previous studies have demonstrated that pharmacokinetic interactions between herbs and anticancer drugs exist due to inhibition of drug−metabolizing enzymes, particularly cytochrome P450s (CYPs). The aim of t...

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Detalles Bibliográficos
Autores principales: Rodseeda, Chumaphorn, Yamanont, Paveena, Pinthong, Darawan, Korprasertthaworn, Porntipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742957/
https://www.ncbi.nlm.nih.gov/pubmed/36518483
http://dx.doi.org/10.1016/j.toxrep.2022.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742957/
https://www.ncbi.nlm.nih.gov/pubmed/36518483
http://dx.doi.org/10.1016/j.toxrep.2022.10.004

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