Sex-dependent sensitivity to positive allosteric modulation of GABA action in an APP knock-in mouse model of Alzheimer's disease: Potential epigenetic regulation

Conflicting evidence suggest that perturbations of GABAergic neurotransmission play crucial roles in disrupting cortical neuronal network oscillations, memory, and cognitive deficits in Alzheimer's disease (AD). However, the role and impact of sex differences on GABAergic transmission in AD are...

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Detalles Bibliográficos
Autores principales: Auta, James, Locci, Andrea, Guidotti, Alessandro, Davis, John M., Dong, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743067/
https://www.ncbi.nlm.nih.gov/pubmed/36518344
http://dx.doi.org/10.1016/j.crneur.2021.100025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743067/
https://www.ncbi.nlm.nih.gov/pubmed/36518344
http://dx.doi.org/10.1016/j.crneur.2021.100025

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