Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids

[Image: see text] Polymyxins are a class of lipopeptide anti-infective agents with potent and specific activity against Gram-negative bacteria. While toxicity concerns associated with polymyxin B and E (colistin) have historically limited their clinical application, today they are increasingly used...

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Detalles Bibliográficos
Autores principales: Slingerland, Cornelis J., Wesseling, Charlotte M. J., Innocenti, Paolo, Westphal, Koen G. C., Masereeuw, Rosalinde, Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743094/
https://www.ncbi.nlm.nih.gov/pubmed/36399613
http://dx.doi.org/10.1021/acs.jmedchem.2c01528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743094/
https://www.ncbi.nlm.nih.gov/pubmed/36399613
http://dx.doi.org/10.1021/acs.jmedchem.2c01528

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