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Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids
[Image: see text] Polymyxins are a class of lipopeptide anti-infective agents with potent and specific activity against Gram-negative bacteria. While toxicity concerns associated with polymyxin B and E (colistin) have historically limited their clinical application, today they are increasingly used...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743094/ https://www.ncbi.nlm.nih.gov/pubmed/36399613 http://dx.doi.org/10.1021/acs.jmedchem.2c01528 |