Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin–p65 interaction

Neuroinflammation is one of the critical processes implicated in central nervous system (CNS) diseases. Therefore, alleviating neuroinflammation has been highlighted as a therapeutic strategy for treating CNS disorders. However, the complexity of neuroinflammatory processes and poor drug transport t...

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Detalles Bibliográficos
Autores principales: Yim, Junhyeong, Lee, Jaeseok, Yi, Sihyeong, Koo, Ja Young, Oh, Sangmi, Park, Hankum, Kim, Seong Soon, Bae, Myung Ae, Park, Jongmin, Park, Seung Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743128/
https://www.ncbi.nlm.nih.gov/pubmed/36509830
http://dx.doi.org/10.1038/s12276-022-00903-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743128/
https://www.ncbi.nlm.nih.gov/pubmed/36509830
http://dx.doi.org/10.1038/s12276-022-00903-z

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