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Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin–p65 interaction
Neuroinflammation is one of the critical processes implicated in central nervous system (CNS) diseases. Therefore, alleviating neuroinflammation has been highlighted as a therapeutic strategy for treating CNS disorders. However, the complexity of neuroinflammatory processes and poor drug transport t...
Autores principales: | Yim, Junhyeong, Lee, Jaeseok, Yi, Sihyeong, Koo, Ja Young, Oh, Sangmi, Park, Hankum, Kim, Seong Soon, Bae, Myung Ae, Park, Jongmin, Park, Seung Bum |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743128/ https://www.ncbi.nlm.nih.gov/pubmed/36509830 http://dx.doi.org/10.1038/s12276-022-00903-z |
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