Role of antibody engineering in generation of derivatives starting from MOv19 MAb: 40 years of biological/therapeutic tools against folate receptor alfa

In the 1980s, we developed and characterized numerous murine monoclonal antibodies (MAbs) directed against human tumor-associated antigens. This mini review is focused on the generation of derivatives of an anti-folate receptor α (FRα) MAbs, named MOv19, exploiting the antibody-engineering progresse...

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Detalles Bibliográficos
Autores principales: Frigerio, Barbara, Montermini, Matilde, Silvana, Canevari, Figini, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743174/
https://www.ncbi.nlm.nih.gov/pubmed/36518225
http://dx.doi.org/10.1093/abt/tbac026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743174/
https://www.ncbi.nlm.nih.gov/pubmed/36518225
http://dx.doi.org/10.1093/abt/tbac026

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