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Conformational Change of Transcription Factors from Search to Specific Binding: A lac Repressor Case Study
[Image: see text] In a process known as facilitated diffusion, DNA-binding proteins find their target sites by combining three-dimensional diffusion and one-dimensional scanning of the DNA. Following the trade-off between speed and stability, agile exploration of DNA requires loose binding, whereas,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743208/ https://www.ncbi.nlm.nih.gov/pubmed/36416228 http://dx.doi.org/10.1021/acs.jpcb.2c05006 |