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The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation

Coronavirus-associated coagulopathy (CAC) is a morbid and lethal sequela of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CAC results from a perturbed balance between coagulation and fibrinolysis and occurs in conjunction with exaggerated activation of monocytes/macrophages...

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Detalles Bibliográficos
Autores principales: Sharma, Sriganesh B., Melvin, William J., Audu, Christopher O., Bame, Monica, Rhoads, Nicole, Wu, Weisheng, Kanthi, Yogendra, Knight, Jason S., Adili, Reheman, Holinstat, Michael A., Wakefield, Thomas W., Henke, Peter K., Moore, Bethany B., Gallagher, Katherine A., Obi, Andrea T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743412/
https://www.ncbi.nlm.nih.gov/pubmed/36493338
http://dx.doi.org/10.1182/blood.2022015917