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The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation
Coronavirus-associated coagulopathy (CAC) is a morbid and lethal sequela of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CAC results from a perturbed balance between coagulation and fibrinolysis and occurs in conjunction with exaggerated activation of monocytes/macrophages...
Autores principales: | Sharma, Sriganesh B., Melvin, William J., Audu, Christopher O., Bame, Monica, Rhoads, Nicole, Wu, Weisheng, Kanthi, Yogendra, Knight, Jason S., Adili, Reheman, Holinstat, Michael A., Wakefield, Thomas W., Henke, Peter K., Moore, Bethany B., Gallagher, Katherine A., Obi, Andrea T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743412/ https://www.ncbi.nlm.nih.gov/pubmed/36493338 http://dx.doi.org/10.1182/blood.2022015917 |
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