Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

[Image: see text] Thiazoles exhibit a wide range of biological activities and therefore represent useful and attractive building blocks. To evaluate their usefulness and pinpoint their liabilities in fragment screening campaigns, we assembled a focused library of 49 fragment-sized thiazoles and thia...

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Detalles Bibliográficos
Autores principales: Proj, Matic, Hrast, Martina, Knez, Damijan, Bozovičar, Krištof, Grabrijan, Katarina, Meden, Anže, Gobec, Stanislav, Frlan, Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743419/
https://www.ncbi.nlm.nih.gov/pubmed/36518695
http://dx.doi.org/10.1021/acsmedchemlett.2c00429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743419/
https://www.ncbi.nlm.nih.gov/pubmed/36518695
http://dx.doi.org/10.1021/acsmedchemlett.2c00429

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