Cargando…

Adolescent triple-negative breast cancer with germline pathogenic variants in both BRCA1 and TP53 genes: A case report

Almost 5-10% of breast cancer results from inherited genetic pathogenic variants. Patients with pathogenic variants in high-penetrance genes such as TP53, BRCA1 and BRCA2 are susceptible to breast cancer. Moreover, nearly 80% of BRCA pathogenic variants carriers are diagnosed with breast cancer at a...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Dongmei, Zhang, Chenyang, Yuan, Mengqi, Zhang, Ying, Liu, Qing, Wan, Donggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743460/
https://www.ncbi.nlm.nih.gov/pubmed/36518309
http://dx.doi.org/10.3389/fonc.2022.970641