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Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma

BACKGROUND: Papillary thyroid cancer (PTC) is the most frequent thyroid tumor. The tissue inhibitor of metalloproteinase-3 (TIMP3) gene encodes a matrix metalloproteinases inhibitor that exerts a tumor suppressor role in several tumor types. TIMP3 is frequently downregulated in PTC by promoter methy...

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Detalles Bibliográficos
Autores principales: Mazzoni, M., Todoerti, K., Agnelli, L., Minna, E., Pagliardini, S., Di Marco, T., Borrello, M. G., Neri, A., Greco, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743531/
https://www.ncbi.nlm.nih.gov/pubmed/36503426
http://dx.doi.org/10.1186/s12935-022-02811-8