Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain

BACKGROUND: Growing evidence shows that C-Type Lectin Domain Containing 7A (Clec7a) may be involved into neuroinflammatory injury of various neurological diseases. However, its roles in neuropathic pain remain unclear. METHODS: A chronic constriction injury (CCI) rat model was constructed, and gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dan, Zhang, Yanqiong, Zhao, Chunhui, Li, Qiuyue, Zhang, Junhong, Han, Jiaxin, Xu, Zhijian, Li, Junfang, Ma, Yan, Wang, Ping, Xu, Haiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743596/
https://www.ncbi.nlm.nih.gov/pubmed/36503542
http://dx.doi.org/10.1186/s12967-022-03779-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743596/
https://www.ncbi.nlm.nih.gov/pubmed/36503542
http://dx.doi.org/10.1186/s12967-022-03779-9

Ejemplares similares