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Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
BACKGROUND: Growing evidence shows that C-Type Lectin Domain Containing 7A (Clec7a) may be involved into neuroinflammatory injury of various neurological diseases. However, its roles in neuropathic pain remain unclear. METHODS: A chronic constriction injury (CCI) rat model was constructed, and gene...
Autores principales: | Wu, Dan, Zhang, Yanqiong, Zhao, Chunhui, Li, Qiuyue, Zhang, Junhong, Han, Jiaxin, Xu, Zhijian, Li, Junfang, Ma, Yan, Wang, Ping, Xu, Haiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743596/ https://www.ncbi.nlm.nih.gov/pubmed/36503542 http://dx.doi.org/10.1186/s12967-022-03779-9 |
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