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Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer’s disease continuum

BACKGROUND: Alzheimer’s disease is characterized by an abnormal increase of phosphorylated tau (pTau) species in the CSF. It has been suggested that emergence of different pTau forms may parallel disease progression. Therefore, targeting multiple specific pTau forms may allow for a deeper understand...

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Detalles Bibliográficos
Autores principales: Gobom, Johan, Benedet, Andréa L., Mattsson-Carlgren, Niklas, Montoliu-Gaya, Laia, Schultz, Nina, Ashton, Nicholas J., Janelidze, Shorena, Servaes, Stijn, Sauer, Mathias, Pascoal, Tharick A., Karikari, Thomas K., Lantero-Rodriguez, Juan, Brinkmalm, Gunnar, Zetterberg, Henrik, Hansson, Oskar, Rosa-Neto, Pedro, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743664/
https://www.ncbi.nlm.nih.gov/pubmed/36510321
http://dx.doi.org/10.1186/s13024-022-00586-0