Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That Exhibits Rapid and Sustained Antidepressant-Like Effects

BACKGROUND: The role of glutamatergic receptors in major depressive disorder continues to be of great interest for therapeutic development. Recent studies suggest that both negative and positive modulation of N-methyl-D-aspartate receptors (NMDAR) can produce rapid antidepressant effects. Here we re...

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Detalles Bibliográficos
Autores principales: Burgdorf, Jeffrey S, Zhang, Xiao-Lei, Stanton, Patric K, Moskal, Joseph R, Donello, John E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743962/
https://www.ncbi.nlm.nih.gov/pubmed/35882204
http://dx.doi.org/10.1093/ijnp/pyac043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743962/
https://www.ncbi.nlm.nih.gov/pubmed/35882204
http://dx.doi.org/10.1093/ijnp/pyac043

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