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Rational Design of a Hybrid Peptide against Severe Acute Respiratory Syndrome Coronavirus 2 Using Melittin and Angiotensin-Converting Enzyme 2 as Pharmaceutical Agents

BACKGROUND: Management of severe acute respiratory syndrome coronavirus 2 in humans depends on the availability of vaccines or effective drugs. Studies have shown that angiotensin-converting enzyme 2 (ACE2) is responsible for binding the viral spike glycoproteins to human cells. Melittin from the be...

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Detalles Bibliográficos
Autores principales: Farhoudi, Ramin, Taheri, Mohammad, Soltani, Minoo, Nezhad Fard, Ramin Mazaheri, Shahedin, Golshid Javdani, Nabian, Sedigheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744085/
https://www.ncbi.nlm.nih.gov/pubmed/36518867
http://dx.doi.org/10.4103/abr.abr_341_21