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Facile and selective N-alkylation of gentamicin antibiotics via chemoenzymatic synthesis
The rise and spread of antimicrobial resistance has necessitated the development of novel antimicrobials which are effective against drug resistant pathogens. Aminoglycoside antibiotics (AGAs) remain one of our most effective classes of bactericidal drugs. However, they are challenging molecules to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744104/ https://www.ncbi.nlm.nih.gov/pubmed/36544494 http://dx.doi.org/10.1039/d2gc03600b |