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Facile and selective N-alkylation of gentamicin antibiotics via chemoenzymatic synthesis

The rise and spread of antimicrobial resistance has necessitated the development of novel antimicrobials which are effective against drug resistant pathogens. Aminoglycoside antibiotics (AGAs) remain one of our most effective classes of bactericidal drugs. However, they are challenging molecules to...

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Detalles Bibliográficos
Autores principales:	Stojanovski, Gorjan, Hailes, Helen C., Ward, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744104/ https://www.ncbi.nlm.nih.gov/pubmed/36544494 http://dx.doi.org/10.1039/d2gc03600b

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