Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α–Syn and tau fragments

INTRODUCTION: Accurate demonstration of phosphorylated α-synuclein aggregation and propagation, progressive nigrostriatal degeneration and motor deficits will help further research on elucidating the mechanisms of Parkinson’s Disease. α-synucleinN103 and tauN368, cleaved by activated asparagine endo...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoman, Wang, Jialing, Zeng, Weiqi, Zhang, Xiaoqian, Yang, Xiaomei, Xu, Yu, Xu, Yan, Cao, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744116/
https://www.ncbi.nlm.nih.gov/pubmed/36518823
http://dx.doi.org/10.3389/fnagi.2022.1049418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744116/
https://www.ncbi.nlm.nih.gov/pubmed/36518823
http://dx.doi.org/10.3389/fnagi.2022.1049418

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