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Young fibroblast-derived exosomal microRNA-125b transfers beneficial effects on aged cutaneous wound healing

Aged skin wounds heal poorly, resulting in medical, economic, and social burdens posed by nonhealing wounds. Age-related defects in repair are associated with reduced myofibroblasts and dysfunctional extracellular matrix (ECM) deposition. Bidirectional cell-cell communication involving exosome-borne...

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Detalles Bibliográficos
Autores principales: Xia, Wenzheng, Li, Minxiong, Jiang, Xingyu, Huang, Xin, Gu, Shuchen, Ye, Jiaqi, Zhu, Liaoxiang, Hou, Meng, Zan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744129/
https://www.ncbi.nlm.nih.gov/pubmed/35305652
http://dx.doi.org/10.1186/s12951-022-01348-2