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Young fibroblast-derived exosomal microRNA-125b transfers beneficial effects on aged cutaneous wound healing
Aged skin wounds heal poorly, resulting in medical, economic, and social burdens posed by nonhealing wounds. Age-related defects in repair are associated with reduced myofibroblasts and dysfunctional extracellular matrix (ECM) deposition. Bidirectional cell-cell communication involving exosome-borne...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744129/ https://www.ncbi.nlm.nih.gov/pubmed/35305652 http://dx.doi.org/10.1186/s12951-022-01348-2 |