Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach

BACKGROUND: Primary congenital glaucoma (PCG) is the most common subtype of glaucoma caused by defects in the cytochrome P450 1B1 (CYP1B1) gene. It is developing among infants in more than 80% of cases who exhibit impairments in the anterior chamber angle and the trabecular meshwork. Thus, a compreh...

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Detalles Bibliográficos
Autores principales: Shahid, Muhammad, Azfaralariff, Ahmad, Tufail, Muhammad, Hussain Khan, Nazeer, Abdulkareem Najm, Ahmed, Firasat, Sabika, Zubair, Muhammad, Fazry, Shazrul, Law, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744154/
https://www.ncbi.nlm.nih.gov/pubmed/36518267
http://dx.doi.org/10.7717/peerj.14132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744154/
https://www.ncbi.nlm.nih.gov/pubmed/36518267
http://dx.doi.org/10.7717/peerj.14132

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