αA and αB peptides from human cataractous lenses show antichaperone activity and enhance aggregation of lens proteins

PURPOSE: To identify and characterize properties of αA- and αB-crystallins’ low molecular weight peptides (molecular weight [Mr] < 5 kDa) that were present in a 62-year-old human nuclear cataract, but not in normal 62-year-old human lenses. METHODS: Low molecular weight peptides (< 5 kDa) were...

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Detalles Bibliográficos
Autores principales: Srivastava, Om, Wilson, Landon, Barnes, Stephen, Srivastava, Kiran, Joseph, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744240/
https://www.ncbi.nlm.nih.gov/pubmed/36540064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744240/
https://www.ncbi.nlm.nih.gov/pubmed/36540064

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