Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization

The nuclear pore complex (NPC) comprises more than 30 nucleoporins (NUPs) and is a hallmark of eukaryotes. NUPs have been suggested to be important in regulating gene transcription and 3D genome organization. However, evidence in support of their direct roles remains limited. Here, by Cut&Run, w...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyu, Qi, Chuangye, Wang, Ruoyu, Lee, Joo-Hyung, Shao, Jiaofang, Bei, Lanxin, Xiong, Feng, Nguyen, Phuoc T., Li, Guojie, Krakowiak, Joanna, Koh, Su-Pin, Simon, Lukas M., Han, Leng, Moore, Travis I., Li, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744245/
https://www.ncbi.nlm.nih.gov/pubmed/36323253
http://dx.doi.org/10.1016/j.celrep.2022.111576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744245/
https://www.ncbi.nlm.nih.gov/pubmed/36323253
http://dx.doi.org/10.1016/j.celrep.2022.111576

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