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Mixed mechanism of conformational selection and induced fit as a molecular recognition process in the calreticulin family of proteins

The fundamental question on the mechanism of molecular recognition during ligand binding has attracted a lot of scientific scrutiny. The two competing theories of ligand binding–“induced fit” and “conformational selection” have been proposed to explain biomolecular recognition. Since exploring a fam...

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Detalles Bibliográficos
Autores principales: Mamidi, Ashalatha Sreshty, Surolia, Avadhesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744295/
https://www.ncbi.nlm.nih.gov/pubmed/36508460
http://dx.doi.org/10.1371/journal.pcbi.1010661