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Identification of possible binding modes of SARS-CoV-2 spike N-terminal domain for ganglioside GM1

Coarse-grained molecular dynamics simulations of the lipid bilayer mixture of POPC and cholesterol were carried out in the presence and absence of ganglioside monosialo 1 (GM1) with N - terminal domain (NTD) of SARS-CoV-2 spike glycoprotein. The interactions of GM1 with two different NTD orientation...

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Detalles Bibliográficos
Autores principales: Das, Tanushree, Mukhopadhyay, Chaitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744490/
https://www.ncbi.nlm.nih.gov/pubmed/36532818
http://dx.doi.org/10.1016/j.cplett.2022.140260