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Single‐Cell Transcriptome Identifies Drug‐Resistance Signature and Immunosuppressive Microenvironment in Metastatic Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a deadly neuroendocrine malignancy with high metastasis. However, the heterogeneity of metastatic SCLC at the single‐cell level remains elusive. The single‐cell transcriptome of a total of 24 081 cells in metastatic lymph node samples from seven SCLC patients via end...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zhang, Haiping, Zhang, Lele, Li, Dianke, Qi, Mengfan, Zhang, Liping, Yu, Huansha, Wang, Di, Jiang, Gening, Wang, Xujun, Zhu, Xianmin, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744506/
https://www.ncbi.nlm.nih.gov/pubmed/36618022
http://dx.doi.org/10.1002/ggn2.202100060