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Facilitating Machine Learning‐Guided Protein Engineering with Smart Library Design and Massively Parallel Assays

Protein design plays an important role in recent medical advances from antibody therapy to vaccine design. Typically, exhaustive mutational screens or directed evolution experiments are used for the identification of the best design or for improvements to the wild‐type variant. Even with a high‐thro...

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Detalles Bibliográficos
Autores principales: Chu, Hoi Yee, Wong, Alan S. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744531/
https://www.ncbi.nlm.nih.gov/pubmed/36619853
http://dx.doi.org/10.1002/ggn2.202100038