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In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein

Cancer cells produce heterogeneous extracellular vesicles (EVs) as mediators of intercellular communication. This study focuses on a novel method to image EV subtypes and their biodistribution in vivo. A red‐shifted bioluminescence resonance energy transfer (BRET) EV reporter is developed, called Pa...

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Detalles Bibliográficos
Autores principales: Perez, Gloria I., Broadbent, David, Zarea, Ahmed A., Dolgikh, Benedikt, Bernard, Matthew P., Withrow, Alicia, McGill, Amelia, Toomajian, Victoria, Thampy, Lukose K., Harkema, Jack, Walker, Joel R., Kirkland, Thomas A., Bachmann, Michael H., Schmidt, Jens, Kanada, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744575/
https://www.ncbi.nlm.nih.gov/pubmed/36619349
http://dx.doi.org/10.1002/ggn2.202100055