Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection

The SARS-CoV-2 infection leads to enhanced inflammation driven by innate immune responses. Upon TLR7 stimulation, dendritic cells (DC) mediate the production of inflammatory cytokines, and in particular of type I interferons (IFN). Especially in DCs, IRF5 is a key transcription factor that regulates...

Descripción completa

Detalles Bibliográficos
Autores principales: Cords, Leon, Woost, Robin, Kummer, Silke, Brehm, Thomas T., Kluge, Stefan, Schmiedel, Stefan, Jordan, Sabine, Lohse, Ansgar W., Altfeld, Marcus, Addo, Marylyn M., Schulze zur Wiesch, Julian, Beisel, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744680/
https://www.ncbi.nlm.nih.gov/pubmed/36529029
http://dx.doi.org/10.1016/j.cyto.2022.156109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744680/
https://www.ncbi.nlm.nih.gov/pubmed/36529029
http://dx.doi.org/10.1016/j.cyto.2022.156109

Ejemplares similares