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Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection

The SARS-CoV-2 infection leads to enhanced inflammation driven by innate immune responses. Upon TLR7 stimulation, dendritic cells (DC) mediate the production of inflammatory cytokines, and in particular of type I interferons (IFN). Especially in DCs, IRF5 is a key transcription factor that regulates...

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Detalles Bibliográficos
Autores principales:	Cords, Leon, Woost, Robin, Kummer, Silke, Brehm, Thomas T., Kluge, Stefan, Schmiedel, Stefan, Jordan, Sabine, Lohse, Ansgar W., Altfeld, Marcus, Addo, Marylyn M., Schulze zur Wiesch, Julian, Beisel, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744680/ https://www.ncbi.nlm.nih.gov/pubmed/36529029 http://dx.doi.org/10.1016/j.cyto.2022.156109

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